The Wealth Index is based on a number of indicators of affluence including average household income and average net worth, but it also includes the value of material possessions and resources. It represents the wealth of the area relative to the national level. Values above or below 100 represent above-average wealth or below-average wealth compared to the national level.
| Name | County | Wealth Index | |
|---|---|---|---|
| 1. | Town of Goodman | Holmes | 13 |
| 2. | Town of Coahoma | Coahoma | 18 |
| 3. | North Tunica Census Designated Place | Tunica | 18 |
| 4. | Town of Lambert | Quitman | 19 |
| 5. | Town of Osyka | Pike | 20 |
| 6. | City of Itta Bena | Leflore | 20 |
| 7. | Town of Arcola | Washington | 21 |
| 8. | Tunica Resorts Census Designated Place | Tunica | 21 |
| 9. | Town of Sledge | Quitman | 22 |
| 10. | Town of Friars Point | Coahoma | 22 |
| 11. | Town of New Augusta | Perry | 22 |
| 12. | Town of Pickens | Holmes | 22 |
| 13. | Lakeview Census Designated Place | DeSoto | 22 |
| 14. | Town of Mayersville | Issaquena | 23 |
| 15. | City of Durant | Holmes | 23 |
| 16. | Town of Brooksville | Noxubee | 23 |
| 17. | Town of Tchula | Holmes | 23 |
| 18. | City of Shelby | Bolivar | 23 |
| 19. | Town of Prentiss | Jefferson Davis | 23 |
| 20. | City of Shaw | Bolivar | 24 |